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Preclinical Innovation Program (PIP) (R01)

Grant Amount: NINIAID/DAIDS intends to commit $3,500,000 in FY 2014 for funding 4 to 8 awards.

This Funding Opportunity Announcement (FOA), the Preclinical Innovation Program (PIP), issued by NIAID, encourages Research Project Grant (R01) applications in non-vaccine biomedical prevention (nBP) research. The PIP is intended to support high risk/innovative research and development efforts designed to establish and maintain a sustainable pipeline of nBP candidates, drug delivery systems (DDS) and supporting technologies for the prevention of HIV acquisition/transmission. The PIP will support novel and under-explored approaches to strengthen and maintain an innovative pipeline of nBP strategies including microbicides, pre-exposure prophylaxis (PrEP), and Multipurpose Prevention Technologies (MPT). To accomplish this, the PIP will also support a range of nBP DDS including, but not limited to, pericoital and sustained delivery of single and combination candidates and strategies using gels, films, intravaginal rings (IVR), oral, implant and/or injection delivery methods. The PIP is a replacement program for the Microbicide Innovation Program ( and investigators are urged to read the current FOA closely to identify critical differences between this and previous programs.
Funding Organization
National Institute of Allergy and Infectious Diseases
Division of Intramural Research
Fund Category
Support Types
Eligible Organizations
City Agencies
Commercial Organizations
Community Based Organizations
County Agencies
Educational Organizations/Institutions
Federal Government Agencies
International Agencies
IRS 501 (c)(3) Organizations
Nonprofit Organizations
Religious Organizations
State Agencies
Tribal Organizations
Number of Awards Given
4 - 8 awards
Award Amount Notes
NIAID/DAIDS intends to commit $3,500,000 in FY 2014 for funding 4 to 8 awards.
Letter of Intent Date
Application Due Date
Project Start Date
Application Contact
Phone: (301) 435-0714
Technical Contact
Jim A Turpin
Phone: (301) 451-2732
Fund Duration
4 years.
HIV/AIDS Prevention
Research Programs
Sexually Transmitted Diseases (STDs)
Application Process
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at

It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (, except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.

Web Site
Fund Number

Disclaimer: NPIN provides this information as a public service only. The views and information provided about the materials, funding opportunities, and organizations do not necessarily state or reflect those of the U.S. Department of Health and Human Services, CDC, or NPIN. Fund Record #4677

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