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Funding

NK Cells to Induce Immunological Memory to Prevent HIV Infection (R01)

Description
Grant Amount: Unspecified.

This Funding Opportunity Announcement (FOA) invites applications to study the immunomodulatory or effector roles of Natural Killer (NK) cells in facilitating and/or regulating the antiviral adaptive immune responses in the context of HIV-1 vaccines. The outcome of these research projects should provide novel approaches to harness NK cell immunoregulatory function in HIV-1 vaccine design and also to enhance protective HIV-1 specific adaptive immune responses.

The primary objective of this funding opportunity is to support multidisciplinary, hypothesis-driven research on NK cells, leading to the discovery of pathways relevant to early immune responses and immune regulation impacting the sought-for protective immunity induced by HIV vaccination. Secondary objectives include the development of novel technologies to allow for more systematic and robust studies of human innate system monitoring in the context of vaccine clinical trials and to enable the recruitment of innate immunologists to the HIV vaccine field.

This initiative will support research to understand the early events triggered by vectored and/or adjuvanted HIV vaccines and the impact of vaccination on the effector/immunoregulatory balance of NK cells.
Funding Organization
National Institute of Allergy and Infectious Diseases
Division of Intramural Research
Fund Category
HIV/AIDS
Support Types
Research
Locations
International
National
Eligible Organizations
City Agencies
Colleges/Universities
Commercial Organizations
Community Based Organizations
County Agencies
Educational Organizations/Institutions
Federal Government Agencies
International Agencies
IRS 501 (c)(3) Organizations
Nonprofit Organizations
Religious Organizations
Schools
State Agencies
Tribal Organizations
Award Amount Notes
The number of awards is contingent upon NIH appropriations and the submission of a sufficient number of meritorious applications.
Application Due Date
5/7/2015
Project Start Date
9/1/2015
Application Contact
GrantsInfo
,
Phone: (301) 435-0714
Technical Contact
Cesar Boggiano
NIAID
Phone: (240) 627-3038
Fund Duration
5 years.
Subjects
HIV/AIDS Prevention
Research Programs
Vaccine Development Research
Audiences
Researchers
Application Process
Applicants must download the SF424 (R&R) application package associated with this funding opportunity using the “Apply for Grant Electronically” button in this FOA or following the directions provided at Grants.gov.

It is critical that applicants follow the instructions in the SF424 (R&R) Application Guide (http://grants.nih.gov/grants/funding/424/SF424_RR_Guide_General_Adobe_VerB.pdf), except where instructed in this funding opportunity announcement to do otherwise. Conformance to the requirements in the Application Guide is required and strictly enforced. Applications that are out of compliance with these instructions may be delayed or not accepted for review.
Web Site
http://grants.nih.gov/grants/guide/pa-files/PA-14-217.html
Fund Number
PA-14-217

Disclaimer: NPIN provides this information as a public service only. The views and information provided about the materials, funding opportunities, and organizations do not necessarily state or reflect those of the U.S. Department of Health and Human Services, CDC, or NPIN.

cdcnpin.org Fund Record #4839

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